Journal Articles

2024

Gress V, Roussy M, Boulianne L, Bilodeau M, Cardin S, ElHachem N, Lisi V, Khakipoor B, Rouette
A, Farah A, Théret L, Aubert L, Fatima F, Audemard É, Thibault P, Bonneil É, Chagraoui J, Laramée L,
Gendron P, Jouan L, Jammali S, Paré B, Simpson SM, Tran TH, Duval M, Teira P, Santiago R, Bittencourt H, Barabé F, Sauvageau G, Smith MA, Hébert J, Roux PP, Gruber TA, Lavallée V-P, Wilhelm BT, Cellot S. CBFA2T3::GLIS2 Pediatric Acute Megakaryoblastic Leukemia is Sensitive to BCL-XL Inhibition by Navitoclax and DT2216. Blood Advances. 2024 8(1): 112-129. https://10.1182/bloodadvances.2022008899

2023

Raghuram N, Nakashima K, Ab Rahman S, Antoniou E, Skajaa T, Merli P, Verma A, Rabin KR, Aftandilian C, Kotecha RS, Cheuk DKL, Jahnukainen K, Kolenova A, Balwierz W, Norton A, O’Brien MM, Cellot S, Chopek A, Arad-Cohen N, Goemans BF, Rojas-Vasquez M, Ariffin H, Bartram J, Kolb EA, Locatelli F, Hasegawa D, Klusmann JH, Hasle H, McGuire B, Sung L, Hitzler JK. Survival Outcomes of Children with Relapsed or Refractory Myeloid Leukemia Associated with Down syndrome. Blood Advances. 2023 7(21): 6532-6539. https://doi.org/10.1182/bloodadvances.2022009381

Beaufils C, Proulx C, Blincoe A, Teira P, Bittencourt H, Cellot S, Duval M, Morin MP, De Bruycker JJ,
Couture J, Samaan K, Decaluwe H, Kleiber N, El Jalbout R, Touzot F, Haddad E, Barsalou J. Case report: Success of Allogeneic Hematopoietic Stem Cell Transplantation for Refractory Systemic-Onset Juvenile Idiopathic Arthritis. Frontiers in Medicine. 2023 10(NA): 1275927. https://doi.org/10.3389/fmed.2023.1275927

Hebert R, Cullinan N, Armstrong L, Blood KA, Brossard J, Brunga L, Cacciotti C, Caswell K, Cellot S, Coltin H, Deyell RJ, Felton K, Fernandez CV, Fleming AJ, Gibson P, Hammad R, Jabado N, Johnston DL, Lafay-Cousin L, Larouche V, Leblanc-Desrochers C, Michaeli O, Perrier R, Pike M, Say J, Schiller I, Toupin AK, Vairy S, van Engelen K, Waespe N, Villani A, Foulkes WD, Malkin D, Reichman L, Goudie C. Performance of the eHealth decision support tool, MIPOGG, for recognising children with Li-Fraumeni, DICER1, Constitutional mismatch repair deficiency and Gorlin syndromes. J Med Genet. 2023 60(12): 1218-1223. https://doi.org/10.1136/jmg-2023-109376

2022

Tran TH, Langlois S, Meloche C, Caron M, Saint-Onge P, Rouette A, Bataille AR, Jimenez-Cortes C,
Sontag T, Bittencourt H, Laverdière C, Lavallée VP, Leclerc JM, Cole PD, Gennarini LM, Kahn JM, Kelly KM, Michon B, Santiago R, Stevenson KE, Welch JJG, Schroeder KM, Koch V, Cellot S, Silverman LB, Sinnett D. Whole-transcriptome analysis in acute lymphoblastic leukemia: a report from the DFCI ALL Consortium Protocol 16-001.Blood Advances. 2022 6(4): 1329-1341. https://doi.org/10.1182/bloodadvances.2021005634

Hubert G, Bittencourt H, Laverdière C, Teira P, Cellot S, Langlois S, Rouette A, Sontag T, Sinnett D, Dal-Soglio D, Turpin S, Tran TH. Clinical response to dabrafenib and chemotherapy in clonally-related histiocytosis and acute lymphoblastic leukemia. Haematologica. 2022 Nov 17. doi: 10.3324/haematol.2022.281926

Sagniez M, Simpson SM, Caron M, Rozendaal M, Pare B, Sontag T, Langlois S, Rouette A, Lavallée VP, Cellot S, Sinnett D, Tran TH, Smith MA. Real-time molecular classification of leukemias. Science Translational Medicine 2022. https://doi.org/10.1101/2022.06.22.22276550

Tibout P, Ledjiar O, Athale U, Rayar M, Kulkarni K, Truong T, Cellot S, Bittencourt H, Pelland-Marcotte MC, Tran TH. Prognostic factors and outcomes of infant acute lymphoblastic leukemia (ALL), hypodiploid ALL, and mixed-phenotype acute leukemia (MPAL) in Canada: a report from CYP-C. Leuk Lymphoma. 2022 63(13): 3208-3216. https://doi.org/10.1080/10428194.2022.2118536

Gourmel A, Rouette A, Benlimame N, El-Jalbout R, Dubé M, Théorêt Y, Piché N, Labonté S, Sinnett D, Cellot S, Dal-Soglio D, Larouche V, Tran TH. Durable Response to Trametinib in an Infant With ERC1-BRAF Infantile Fibrosarcoma-Like Tumor: A Case Report and Literature Review of BRAF-Altered Infantile Fibrosarcoma-Like Tumors. JCO Precis Oncol. 2022 Aug;6:e2200200. doi: 10.1200/PO.22.00200

2021

Pincez T, Santiago R, Bittencourt H, Louis I, Bilodeau M, Rouette A, Jouan L, Landry, JR, Couture
F, Richer J, Teira P, Duval M, Cellot S. Intensive monitoring of minimal residual disease and
chimerism after allogeneic hematopoietic stem cell transplantation for acute leukemia in children. Bone Marrow Transplantation. 2021 56(NA): 2981–2989. https://doi.org/10.1038/s41409-021-01408-5

Vairy S, , Louis I, Vachon M-F, Richer J, Teira P, Cellot S, Villeneuve E, Haddad E, Duval M, Bittencourt H. Intrabone Infusion for Allogeneic Umbilical Cord Blood Transplantation in Children. Bone Marrow Transplantation. 2021 56: 1937–1943. https://doi.org/10.1038/s41409-021-01275-0

Beaufils C, Fernandez I, Marchitto L, Morin M-P, De Bruycker J-J, Cellot S, Soucy J-F, Ovetchkine P,
Oligny L, Haddad E, Touzot F. Multicentric Castleman disease revealing complete signal transducer and activator of transcription 1 deficiency treated by JAK1/2 inhibition. J Allergy Clin Immunol Pract. 2021 9(10):3838-3840.e1. https://doi.org/10.1016/j.jaip.2021.06.031

Marois L, Touzot F, Haddad E, Fernandez I, Morin M-P, De Bruycker JJ, Duval M, Cellot S,
Teira P, Bittencourt H, Decaluwe H. Successful management of familial hemophagocytic
lymphohistiocytosis by the JAK 1/2 inhibitor ruxolitinib. Pediatric Blood & Cancer. 2021 68(6): e28954. doi: 10.1002/pbc.28954

Goudie C, Witkowski L, Cullinan N, Reichman L, Schiller I, Tachdjian M, Armstrong L, Blood KA, Brossard J, ; Brunga L, Cacciotti C, Caswell K, Cellot S, Clark ME, Clinton C, Coltin H, Felton K, Fernandez CV, Fleming AJ, Fuentes-Bolanos N, Gibson P, Grant R, Hammad R, Harrison LW, Irwin MS, Johnston DL, Kane S, Lafay-Cousin L, Lara-Corrales I, Larouche V, Mathews N, Meyn SM, Michaeli O, Perrier R, Pike M, Punnett A, Ramaswamy V, Say J, Somersm G, Tabori U, Thibodeau ML, Toupin A-K, Tucker KM, van Engelen K, Vairy S, Waespe N, Warby M, Wasserman JD, Whitlock JA, Sinnett D, Nada Jabado, Nathan PC, Shlien A, Kamihara J, Deyell RJ, Ziegler DS, Nichols KE, Dendukuri N, Malkin D, Villani A, Foulkes WD. Performance of the McGill Interactive Pediatric OncoGenetic Guidelines for Identifying Cancer Predisposition Syndromes. JAMA Oncol. 2021 7(12): 1806–1814. doi:10.1001/jamaoncol.2021.4536

2020

Pincez T, Landry JR, Roussy M, Jouan L, Bilodeau M, Laramée L, Couture F, Sinnett D, Gendron P, Hébert J, Oligny L, Rouette A, Tran TH, Wilhelm BT, Bittencourt H, Cellot S. Cryptic recurrent ACIN1-NUTM1 fusions in non-KMT2A-rearranged infant acute lymphoblastic leukemia. Genes Chromosomes Cancer. 2020 Feb;59(2):125-130. https://doi.org/10.1002/gcc.22808

2019

Khater F, Vairy S, Langlois S, Dumoucel S, Sontag T, St-Onge P, Bittencourt H, Dal Soglio D, Champagne J, Duval M, Leclerc JM, Laverdiere C, Tran TH, Patey N, Ellezam B, Perreault S, Piché N, Samson Y, Teira P, Jabado N, Michon B, Brossard J, Marzouki M, Cellot S, Sinnett D. Molecular Profiling of Hard-to-Treat Childhood and Adolescent Cancers. JAMA Netw Open. 2019 Apr 5;2(4). doi:10.1001/jamanetworkopen.2019.2906

Milan T, Canaj H, Villeneuve C, Ghosh A, Barabé F, Cellot S, Wilhelm BT. Pediatric leukemia: Moving toward more accurate models. Exp Hematol. 2019 Jun;74:1-12. doi:10.1016/j.exphem.2019.05.003

Cardin S, Bilodeau M, Roussy M, Aubert L, Milan T, Jouan L, Rouette A, Laramée L, Gendron P, Duchaine J, Decaluwe H, Spinella JF, Mourad S, Couture F, Sinnett D, Haddad É, Landry JR, Ma J, Humphries RK, Roux PP, Hébert J, Gruber TA, Wilhelm BT, Cellot S. Human models of NUP98-KDM5A megakaryocytic leukemia in mice contribute to uncovering new biomarkers and therapeutic vulnerabilities. Blood Adv. 2019 Nov 12;3(21):3307-3321. doi:10.1182/bloodadvances.2019030981

Mourad S, Bilodeau M, Roussy M, Laramée L, Boulianne L, Rouette A, Jouan L, Gendron P, Duval M, Teira P, Hébert J, Bittencourt H, Pastore Y, Landry JR, Cellot S. IDH1 as a Cooperating Mutation in AML Arising in the Context of Shwachman-Diamond Syndrome. Front Oncol. 2019 Aug 14;9:772. doi:10.3389/fonc.2019.00772

Gatineau-Sailliant S, Turcotte K, Quintal MC, Turpin S, Champagne J, Petrella T, Roussy M, Cellot S, Bouron-Dal Soglio D. Gray Zone Lymphoma Arising in the Neck of a Teenager With a Germline Mutation in TP53. J Pediatr Hematol Oncol. 2019 Aug;41(6):e405-e408. doi:10.1097/MPH.0000000000001308

2018

Roussy M, Bilodeau M, Jouan L, Tibout P, Laramée L, Lemyre E, Léveillé F, Tihy F, Cardin S, Sauvageau C, Couture F, Louis I, Choblet A, Patey N, Gendron P, Duval M, Teira P, Hébert J, Wilhelm BT, Choi JK, Gruber TA, Bittencourt H, Cellot S. NUP98-BPTF gene fusion identified in primary refractory acute megakaryoblastic leukemia of infancy. Genes Chromosomes Cancer. 2018 Jun;57(6):311-319. doi:10.1002/gcc.22532

Benadiba J, Ansari M, Krajinovic M, Vachon MF, Duval M, Teira P, Cellot S, Bittencourt H. Pharmacokinetics-adapted Busulfan-based myeloablative conditioning before unrelated umbilical cord blood transplantation for myeloid malignancies in children. PLoS One. 2018 Apr 2;13(4):e0193862. doi:10.1371/journal.pone.0193862

Vairy S, Jouan L, Bilodeau M, Dormoy-Raclet V, Gendron P, Couture F, Léveillé F, Tihy F, Lemyre E, Soglio DB-D, Jabado N, Kleinman CL, Marzouki M, Cellot S. (2018). Novel PDE10A-BRAF Fusion With Concomitant NF1 Mutation Identified in an Undifferentiated Sarcoma of Infancy With Sustained Response to Trametinib. JCO Precision Oncology. 2: 1-13. http://dx.doi.org/https://doi.org/10.1200/PO.18.00007

2017

Cellot S, Wilhelm BT, Barabé F. Synthetic human leukemia models: towards precision medicine. Oncotarget. 2017;8(57):96480–96481. Published 2017 Nov 2. doi:10.18632/oncotarget.22259

Lagacé K, Barabé F, Hébert J, Cellot S, Wilhelm BT. Identification of novel biomarkers for MLL-translocated acute myeloid leukemia. Exp Hematol. 2017 Dec;56:58-63. doi:10.1016/j.exphem.2017.08.006

Barabé F, Gil L, Celton M, Bergeron A, Lamontagne V, Roques É, Lagacé K, Forest A, Johnson R, Pécheux L, Simard J, Pelloux J, Bellemare-Pelletier A, Gagnon E, Hébert J, Cellot S, Wilhelm BT. Modeling human MLL-AF9 translocated acute myeloid leukemia from single donors reveals RET as a potential therapeutic target. Leukemia. 2017 May;31(5):1166-1176. https://doi.org/10.1038/leu.2016.302